Low-level ozone has both respiratory and systemic effects in African American adolescents with asthma despite asthma controller therapy.

Center for Environmental Medicine, Asthma, and Lung Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC; Division of Allergy, Immunology, and Rheumatology, Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, NC. Electronic address: michelle_hernandez@med.unc.edu. US Environmental Protection Agency, National Health and Environmental Effects Research Laboratory, Chapel Hill, NC. Center for Environmental Medicine, Asthma, and Lung Biology, University of North Carolina at Chapel Hill, Chapel Hill, NC; Division of Allergy, Immunology, and Rheumatology, Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, NC. Division of Pulmonology, Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, NC. Merck, Kenilworth, NJ.